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Invitrogen
HMGN2 Polyclonal Antibody
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HMGN2 Antibody (PA5-95559) in IHC (P)
Immunohistochemistry analysis of HMGN2 in paraffin-embedded human esophagus squama cancer tissue. Antigen retrieval was performed on the tissue using citrate buffer (pH 6, 20 min) and blocked with 10% goat serum. Samples were incubated with HMGN2 polyclonal antibody (Product # PA5-95559) at a 2 µg/mL dilution, followed by biotinylated goat anti-rabbit IgG (30 min, 37°C), and developed with Strepavidin-Bioti... View More
产品信息
PA5-95559
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence of human HMGN2 (KKGKADAGKEGNNPAENGDAKTDQAQKAEGAGDAK).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Affinity chromatography
保存液
PBS with 4mg trehalose
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human SH-SY5Y whole cell, human HL-60 whole cell. IHC: human rectal cancer tissue, human tonsil tissue, human thyroid cancer tissue, human liver cancer tissue. ICC/IF: MCF7 cell. Flow: Raji cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: High mobility group nucleosome-binding domain-containing protein 2; high mobility group protein N2; high-mobility group (nonhistone chromosomal) protein 17; high-mobility group nucleosomal binding domain 2; Non-histone chromosomal protein HMG-17; nonhistone chromosomal protein HMG-17
基因别名: HMG17; HMGN2
UniProt ID: (Human) P05204
Entrez Gene ID: (Human) 3151
