应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
1 µg/mL | - |
免疫组化 (IHC) |
10-20 µg/mL | 查看1篇已发表文章 1篇已发表文章 |
酶联免疫吸附实验 (ELISA) |
3 µg/mL | - |
免疫沉淀 (IP) |
Assay-dependent | - |
产品规格 | |
---|---|
种属反应 |
Human, Rat |
已发表种属 |
Human |
宿主/亚型 |
Mouse / IgG1 |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
H6939 |
抗原 |
Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human HNF4--alpha (1-16 aa). |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Ammonium sulfate precipitation |
保存液 |
physiological saline |
内含物 |
0.1% sodium azide |
保存条件 |
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C |
RRID |
AB_2532198 |
This antibody specifically recognizes human HNF4 alpha 7- 9 and cross reacts with mouse and rat HNF4 alpha 7- 9.
Hepatocyte nuclear factor 4 alpha (HNF4 alpha) is an orphan nuclear receptor. HNF4a is expressed in the liver, kidney, intestine, and pancreas. Mutation of HNF4a in humans has been associated with maturity-onset diabetes of the young type 1 (MODY1). HNF4 binds to DNA as an exclusive homodimer. The HNF4a gene is alternatively spliced and may generate up to nine different isoforms, HNF4a1 through HNF4a9.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: alpha transcription factor 4; FLJ39654; hepatic nuclear factor 4 alpha; hepatic nuclear factor 4, alpha; hepatocyte nuclear factor 4, alpha; Hepatocyte nuclear factor 4-alpha; HNF-4-alpha; HNF4-alpha; HNF4alpha10/11/12; Nuclear receptor subfamily 2 group A member 1; TCF-14; Transcription factor 14; Transcription factor HNF-4
基因别名: FRTS4; Hnf-4; HNF4; HNF4A; HNF4a7; HNF4a8; HNF4a9; HNF4alpha; MODY; MODY1; NR2A1; NR2A21; TCF; TCF14
UniProt ID: (Human) P41235, (Rat) P22449
Entrez Gene ID: (Human) 3172, (Rat) 25735
分子生物学功能:
C4 zinc finger nuclear receptor