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Proteintech
HOMER3 Polyclonal Antibody
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产品信息
16624-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
HOMER3 Fusion Protein Ag9923 (1-361 aa encoded by BC012113)
偶联物
形式
Liquid
浓度
0.28 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSTAREQPI FSTRAHVFQI DPATKRNWIP AGKHALTVSY FYDATRNVYR IISIGGAKAI INSTVTPNMT FTKTSQKFGQ WADSRANTVY GLGFASEQHL TQFAEKFQEV KEAARLAREK SQDGGELTSP ALGLASHQVP PSPLVSANGP GEEKLFRSQS ADAPGPTERE RLKKMLSEGS VGEVQWEAEF FALQDSNNKL AGALREANAA AAQWRQQLEA QRAEAERLRQ RVAELEAQAA SEVTPTGEKE GLGQGQSLEQ LEALVQTKDQ EIQTLKSQTG GPREALEAAE REETQQKVQD LETRNAELEH QLRAMERSLE EARAERERAR AEVGRAAQLL DVRLFELSEL REGLARLAEA AP (1-361 aa encoded by BC012113)
靶标信息
This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: homer homolog 3; Homer protein homolog 3; Homer, neuronal immediate early gene, 3; Homer-3; VASP/Ena-related gene up-regulated during seizure and LTP 3; Vesl-3
基因别名: AW146114; HOMER-3; HOMER3; Vesl-3; VESL3
UniProt ID: (Human) Q9NSC5, (Mouse) Q99JP6, (Rat) Q9Z2X5
Entrez Gene ID: (Human) 9454, (Mouse) 26558, (Rat) 29548
