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Proteintech
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Immunogen sequence: QVQDLHVKL SSESKRADTL AFEMKRLEEK HEALLKEKER LIEQRDTLKE TNEELRCSQV QQDHLNQTDA SATKSYENLA AEIMPVEYRE VFIRLQHENK MLRLQQEGSE NERIEELQEQ LEQKHRKMNE LETEQRLSKE RIRELQQQIE DLQKSLQEQG SKSEGESSSK LKQKLEAHME KLTEVHEELQ KKQELIEDLQ PDINQNVQKI NELEAALQKK DEDMKAMEER YKMYLEKARN VIKTLDPKLN PASAEIMLLR KQLAEKERRI EILESECKVA KFRDYEEKLI VSAWYNKSLA FQKLGMESRL VSGGGACSDT GACTPARSFL AQQRHITNTR RNLSVKVPAT TSD (377-728 aa encoded by BC011621)
This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: abnormal spermatozoon head shape; h-hook1; hHK1; hook homolog 1; mHK1; Protein Hook homolog 1
基因别名: A930033L17Rik; azh; HK1; HOOK1
UniProt ID: (Human) Q9UJC3, (Mouse) Q8BIL5
Entrez Gene ID: (Human) 51361, (Mouse) 77963