应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫组化(石蜡) (IHC (P)) |
5-10 µg/mL | - |
产品规格 | |
---|---|
种属反应 |
Human |
宿主/亚型 |
Goat / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Peptide with sequence PQATSCSFAQNIKE, from the internal region of HOXA10 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.5 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
TBS, pH 7.3, with 0.5% BSA |
内含物 |
0.02% sodium azide |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2554474 |
This antibody is predicted to react with mouse, pig and cow based on sequence homology.
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factorm HOXA10, that may regulate gene expression, morphogenesis, and differentiation. More specifically, HOXA10 may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the downstream homeobox A9 gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: homeo box A10; homeobox protein 1H; Homeobox protein Hox-1.8; Homeobox protein Hox-1H; Homeobox protein Hox-A10; homeobox protein HOXA10; Hox-18; PL
基因别名: HOX1; HOX1.8; HOX1H; HOXA10; PL
UniProt ID: (Human) P31260
Entrez Gene ID: (Human) 3206
分子生物学功能:
helix-turn-helix transcription factor
homeodomain transcription factor
DNA-binding transcription factor
gene-specific transcriptional regulator