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Invitrogen
HOXB7 Polyclonal Antibody
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HOXB7 Antibody (PA5-48725) in IHC (P)
Immunohistochemical analysis of Mouse Hoxb7 in formalin fixed and paraffin embedded mouse jejunum tissue. Samples stained using a Mouse Hoxb7 Antibody (Center) (Product # PA5-48725), followed by peroxidase conjugation of the secondary antibody and DAB staining.
产品信息
PA5-48725
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 94-122 amino acids from the Central region of mouse Hoxb7.
偶联物
形式
Liquid
浓度
Lot-Specific
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
Predicted to react with bovine and rat based on sequence homology.
靶标信息
The homeobox genes encode transcription factors that regulate developmental processes such as body patterning and organogenesis. The mammalian HOX gene complex consists of 39 genes that are located on 4 linkage groups (clusters), dispersed over 4 chromosomes (HOXA, HOXB, HOXC and HOXD). HOXB7 is expressed in most malignant T-cell lines and CD4-positive peripheral blood cells, and is constitutively expressed in both melanoma primary lesions and cell lines. HOXB7 binds to and transactivates bFGF in melanoma cell lines but SkBr3 breast adenocarcinoma is negative for the expression of both HOXB7 and bFGF genes. HOXB7 may be a key activator of tumor-associated neoangiogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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