应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
1-5 µg/mL | - |
免疫细胞化学 (ICC/IF) |
5-10 µg/mL | - |
酶联免疫吸附实验 (ELISA) |
Assay-Dependent | - |
产品规格 | |
---|---|
种属反应 |
Human, Rat |
宿主/亚型 |
Mouse / IgG2a, kappa |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
4E12 |
抗原 |
CBX1 (NP_006798.1, 2 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Affinity chromatography |
保存液 |
PBS, pH 7.4 |
内含物 |
no preservative |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2608236 |
Peptide Sequence: GKKQNKKKVE EVLEEEEEEY VVEKVLDRRV VKGKVEYLLK WKGFSDEDNT WEPEENLDCP DLIAEFLQSQ KTAHETDKSE GGKRKADSDS EDKGEESK
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: chromobox homolog 1; chromobox homolog 1 (HP1 beta homolog Drosophila ); Chromobox protein homolog 1; Heterochromatin protein 1 homolog beta; heterochromatin protein 1-beta; Heterochromatin protein p25; heterochromatin protein p25 beta; HGNC:1551; HP1 beta; HP1 beta homolog; HP1Hsbeta; M31; Modifier 1 protein; p25beta
基因别名: CBX; CBX1; HP1-BETA; HP1Hs-beta; HP1Hsbeta; M31; MOD1; p25beta
UniProt ID: (Human) P83916
Entrez Gene ID: (Human) 10951, (Rat) 360609