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Invitrogen
HPS3 Polyclonal Antibody
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HPS3 Antibody (PA5-115380) in IHC (P)
Immunohistochemistry analysis of HPS3 in mouse liver tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115380) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
产品信息
PA5-115380
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human HPS3(Accession Q969F9), corresponding to amino acid residues S537-V587.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total HPS3.
靶标信息
This gene encodes a protein containing a potential clathrin-binding motif, consensus dileucine signals, and tyrosine-based sorting signals for targeting to vesicles of lysosomal lineage. The encoded protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 3. Alternate splice variants exist, but their full length sequence has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BLOC-2 complex member HPS3; cocoa; Cocoa protein; DKFZp686F0413; FLJ22704; Hermansky-Pudlak syndrome 3 protein; Hermansky-Pudlak syndrome 3 protein homolog
基因别名: BLOC2S1; Coa; HPS3; SUTAL
UniProt ID: (Human) Q969F9, (Mouse) Q91VB4
Entrez Gene ID: (Human) 84343, (Mouse) 12807, (Rat) 310288
