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PA1-20556 detects Histamine H3 Receptor in Human samples.
PA1-20556 has been successfully used in Immunohistochemistry (Paraffin) procedures.
PA1-20556 immunogen corresponds to Synthetic peptide (aa sequence is considered to be commercially sensitive).
H3 Histamine Receptor regulates the release of the neurotransmitters norepinephrine and somatostatin. In histamine-containing neurons of the brain, the H3 receptor acts as a presynaptic autoreceptor, while in nonhistamine-containing neurons, in both the central and peripheral nervous systems, it acts as a presynaptic heteroreceptor. Multiple isoforms of H3 receptors are produced by alternative splicing. Histamine H3 receptor has been reported primarily in brain. ESTs have been isolated from brain (normal and cancer), breast cancer, colon cancer, and retinoblastoma libraries.
仅用于科研。不用于诊断过程。未经明确授权不得转售。