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Invitrogen
HRH3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-33846
产品规格
种属反应
Bovine,
Horse,
Guinea pig,
Hamster,
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 16 amino acid peptide from 2nd cytoplasmic domain of human HRH3 / Histamine H3 Receptor.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
50 µg
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is not recommended for use in WB applications.
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Rat, Hamster, Elephant, Bovine, Horse, Guinea pig (100%).
靶标信息
H3 Histamine Receptor regulates the release of the neurotransmitters norepinephrine and somatostatin. In histamine-containing neurons of the brain, the H3 receptor acts as a presynaptic autoreceptor, while in nonhistamine-containing neurons, in both the central and peripheral nervous systems, it acts as a presynaptic heteroreceptor. Multiple isoforms of H3 receptors are produced by alternative splicing. Histamine H3 receptor has been reported primarily in brain. ESTs have been isolated from brain (normal and cancer), breast cancer, colon cancer, and retinoblastoma libraries.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: experimental allergic encephalomyelitis susceptibility 8; G protein-coupled receptor 97; G-protein coupled receptor; G-protein coupled receptor; HRH3S; GPCR; H3R; HH3R; Histamine H3 receptor; histamine H3 receptor H3L isoform; histamine receptor; histamine receptor H 3; histamine receptor H3; MRH3; truncated GPCR; unnamed protein product
基因别名: Eae8; GPCR97; H3R; HH3R; I79_009854
UniProt ID: (Human) Q9Y5N1, (Mouse) P58406, (Guinea pig) Q9JI35, (Rat) Q9QYN8
Entrez Gene ID: (Horse) 100058016, (Human) 11255, (Mouse) 99296, (Guinea pig) 100135541, (Chinese hamster) 100764853, (Rat) 85268
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway
chemical synaptic transmission
neurotransmitter secretion
negative regulation of adenylate cyclase activity
positive regulation of cytosolic calcium ion concentration
learning
memory
negative regulation of glutamate secretion
negative regulation of gamma-aminobutyric acid secretion
regulation of norepinephrine secretion
negative regulation of serotonin secretion
eating behavior
drinking behavior
negative regulation of blood pressure
cAMP metabolic process
positive regulation of epithelial cell proliferation
cognition
positive regulation of arachidonic acid secretion
response to forskolin
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