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Invitrogen
HSP27 Monoclonal Antibody (G3.1), Biotin
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HSP27 Antibody (MA5-11213) in WB
Knockdown of HSP27 / Heat Shock Protein 27 was achieved by transfecting HeLa cells with HSP27 / Heat Shock Protein 27 specific siRNAs (Silencer® select Product # s194537 and s6991). Western blot analysis (Fig a) was performed using whole cell extract from the HSP27 / Heat Shock Protein 27 knock down cells (lane 3), non-specific scrambled siRNA transfected cells (lane 2) and untransfected cells (lane 1). The blots were probed with Anti-HSP27 / Heat Shock Protein 27 Biotin Mouse Monoclonal Antibody (Product # MA5-11213, 1ug/mL) and Poly-HRP ... View More
产品信息
MA5-11213
应用
建议稀释比
已发表文章
产品规格
已发表种属
Human,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
G3.1
抗原
Partially purified hsp27 (earlier called 24K) protein from breast cancer MCF-7 cells
偶联物
形式
Liquid
浓度
0.2 mg/mL
规格
100 µg
保存条件
4°C
运输条件
Wet ice
RRID
产品详细信息
MA5-11213 targets Heat Shock Protein 27 in IHC (P) and WB applications and shows reactivity with Human and Non-human primate samples.
The MA5-11213 immunogen is partially purified hsp27 (earlier called 24K) protein from breast cancer MCF-7 cells.
靶标信息
In response to adverse changes in their environment, cells from many organisms increase the expression of a class of proteins referred to as heat shock or stress proteins. HSPB1 (heat shock protein beta-1 or HSP27) is a small heat shock protein which functions as a molecular chaperone that maintains denatured proteins in a folding-competent state. It plays a role in stress resistance and actin organization. Through its molecular chaperone activity, HSP27 regulates numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins. Mutations in the gene can result in Charcot-Marie-Tooth disease 2F and Neuronopathy distal hereditary motor 2B.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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