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Invitrogen
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Immunogen sequence: AKDVKFGADA RALMLQGVDL LADAVAVTMG PKGRTVIIEQ SWGSPKVTKD GVTVAKSIDL KDKYKNIGAK LVQDVANNTN EEAGDGTTTA TVLARSIAKE GFEKISKGAN PVEIRRGVML AVDAVIAELK KQSKPVTTPE EIAQVATISA NGDKEIGNII SDAMKKVGRK GVITVKDGKT LNDELEIIEG MKFDRGYISP YFINTSKGQK CEFQ; Positive Samples: HeLa, Jurkat, K-562, Mouse kidney, Mouse liver, Mouse thymus, Rat heart; Cellular Location: Mitochondrion matrix
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.
仅用于科研。不用于诊断过程。未经明确授权不得转售。