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Antibody detects endogenous levels of total HTATSF1.
The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 17S U2 SnRNP complex component HTATSF1; cofactor required for Tat activation of HIV-1 transcription; HIV TAT specific factor 1; HIV Tat-specific factor 1; HIV Tat-specific factor 1 homolog; RP1-196E23.2; Tat-SF1
基因别名: 1600023H17Rik; 2600017A12Rik; 2700077B20Rik; dJ196E23.2; HTATSF1; RGD1563377; TAT-SF1; TATSF1
UniProt ID: (Human) O43719, (Mouse) Q8BGC0
Entrez Gene ID: (Human) 27336, (Rat) 317612, (Mouse) 72459
分子生物学功能: RNA splicing factor RNA metabolism protein RNA processing factor nucleic acid metabolism protein