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Invitrogen
HTR2B (extracellular) Polyclonal Antibody
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HTR2B (extracellular) Antibody (PA5-77749) in IHC
Immunohistochemistry analysis of HTR2B (extracellular) in mouse cerebellum. A) Samples were probed with HTR2B (extracellular) polyclonal antibody (Product # PA5-77749) using a dilution of 1:400, and incubated with DAPI (red). B) Nuclei stained image. C) Merged image of Panels A and B.
产品信息
PA5-77749
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide (C)KMSEQ STISEHILQK, corresponding to amino acid residues 6-20 of rat 5-hydroxytryptamine receptor 2B
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.
靶标信息
HTR2B is a g-protein coupled receptor for 5-hydroxytryptamine (serotonin). It functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. HTR2B also plays a role in perception of pain, regulation of behavior. It is required to normal proliferation of embryonic cardiac myocytes and normal heart development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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