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Invitrogen
HTRA3 Polyclonal Antibody
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产品信息
PA5-110869
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: ITRFLTEFQD KQIKDWKKRF IGIRMRTITP SLVDELKASN PDFPEVSSGI YVQEVAPNSP SQRGGIQDGD IIVKVNGRPL VDSSELQEAV LTESPLLLEV RRGNDDLLFS IAP
Highest antigen sequence indentity to the following orthologs: Mouse - 89%, Rat - 90%.
靶标信息
HtrA3 belongs to the human high-temperature requirement factor A (HtrA) family. It is also called pregnancy-related serine protease. HtrA3 has two isoforms (long and short), which is produced by alternative splicing. Similar to HtrA1, HtrA3 binds to various TGF-beta proteins and inhibited the signaling of BMP-4, -2 and TGF-beta 1. HtrA3 does not inhibit signaling originated from a constitutively active BMP receptor, indicating that the inhibition occurred upstream of the cell surface receptor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: High-temperature requirement factor A3; Pregnancy-related serine protease; probable serine protease HTRA3; Serine protease HTRA3
基因别名: HTRA3; PRSP; Tasp
UniProt ID: (Human) P83110
Entrez Gene ID: (Human) 94031
