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Proteintech
HYAL2 Polyclonal Antibody
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产品信息
51148-1-AP
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
HYAL2 Fusion Protein Ag0582 (1-280 aa encoded by BC000692)
偶联物
形式
Liquid
浓度
1.5 mg/mL
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MRAGPGPTV TLALVLAVAW AMELKPTAPP IFTGRPFVVA WDVPTQDCGP RLKVPLDLNA FDVQASPNEG FVNQNITIFY RDRLGLYPRF DSAGRSVHGG VPQNVSLWAH RKMLQKRVEH YIRTQESAGL AVIDWEDWRP VWVRNWQDKD VYRRLSRQLV ASRHPDWPPD RIVKQAQYEF EFAAQQFMLE TLRYVKAVRP RHLWGFYLFP DCYNHDYVQN WESYTGRCPD VEVARNDQLA WLWAESTALF PSVYLDETLA SSRHGRNFVS FRVQEALRVA R (1-280 aa encoded by BC000692)
靶标信息
This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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