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产品信息
PA5-50427
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:500-1:2,000 | - |
免疫组化（石蜡） (IHC (P)) |
1:50-1:200 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Fusion protein corresponding to a region derived from internal residues of human hyaluronoglucosaminidase 3 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1.6 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 40% glycerol |
内含物 |
0.05% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2635880 |
产品详细信息
The antibody detects endogenous levels of total HYAL3 protein.
靶标信息
This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Hyal-3; Hyaluronidase-3; Hyaluronoglucosaminidase-3; LuCa-3; LUCA14; Lung carcinoma protein 3; Minna14
基因别名: HYAL-3; HYAL3; LUCA-3; LUCA3
UniProt ID: (Human) O43820
Entrez Gene ID: (Human) 8372
分子生物学功能:
glycosidase
