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Invitrogen
Histone H1.4 Recombinant Rabbit Monoclonal Antibody (22H6L6)
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
图: 1 / 4
Histone H1.4 Antibody (702876) in WB
Western blot analysis was performed on acid extracts (20 µg lysate) of NTERA-2 (Lane 1), Hep G2 (Lane 2), MCF7 (Lane 3), U-2 OS (Lane 4), HT-29 (Lane 5) and HCT 116 (Lane 6). The blot was probed with Anti-H1.4 Recombinant Rabbit Monoclonal Antibody (Product # 702876, 1:1,000 dilution) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.25 µg/mL, 1:4,000 dilution). A 35 kDa band corresponding to H1.4 was observed across the cell lines tested.
产品信息
702876
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
22H6L6
抗原
Peptides corresponding to human H1.4 [1) aa21-aa33 2) aa164-aa176]
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2762376
产品详细信息
This antibody is predicted to react with Monkey, Bovine, Pig.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: H1 histone family, member 4; h1e; histone 1, H1e; Histone cluster 1; Histone H1.4; Histone H1b; Histone H1s-4; MGC116819
基因别名: dJ221C16.5; H1-4; H1.4; H1E; H1F4; H1s-4; HIST1H1E
UniProt ID: (Human) P10412
Entrez Gene ID: (Human) 3008
