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产品信息
PEP-0361
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
对照试剂 (Ctrl) |
Assay-dependent | - |
阻断反应 (BLOCK) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
分类 |
Synthetic |
类型 |
Peptide |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
200 µg/mL |
纯化类型 |
purified |
保存液 |
PBS, pH 7.2, with 0.1% BSA |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
产品详细信息
This peptide corresponds to 13 amino acids near the carboxy terminus of human AIM.
PEP-0361 can be used as a blocking peptide with polyclonal antibody PA5-20242.
靶标信息
Apoptosis inhibitor of macrophages (AIM) is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5. It was shown that AIM functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection. AIM was also shown to support macrophage survival and enhance their phagocytic function. More recent experiments using recombinant AIM significantly inhibited apoptosis of NKT and T cells obtained from C. parvum-stimulated livers in vitro, suggesting that AIM functions to induce resistance to apoptosis in these cells and supports host defense against inflammation during infection.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: apoptosis inhibitor 6; Apoptosis inhibitor expressed by macrophages; apoptosis inhibitor of macrophage; APOPTOSIS INHIBITOR OF MACROPHAGES; CD5 antigen like (scavenger receptor cysteine rich family); CD5 antigen-like; CD5 antigen-like (scavenger receptor cysteine rich family); CD5 molecule-like; CT-2; hAIM; Highly similar to ANTIGEN WC1.1 [Bos taurus]; IgM-associated peptide; SCAVENGER RECEPTOR CYSTEINE-RICH FAMILY; SP-alpha
基因别名: AIM; API6; CD5L; CT-2; hAIM; PRO229; SP-ALPHA; Spalpha; UNQ203/PRO229
UniProt ID: (Human) O43866
Entrez Gene ID: (Human) 922
