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产品信息
PEP-1020
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
对照试剂 (Ctrl) |
Assay-dependent | - |
阻断反应 (BLOCK) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Not Applicable |
分类 |
Synthetic |
类型 |
Peptide |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
200 µg/mL |
纯化类型 |
purified |
保存液 |
PBS, pH 7.2, with 0.1% BSA |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
产品详细信息
This peptide corresponds to 18 amino acids near the amino terminus of human BCAS3.
PEP-1020 can be used as a blocking peptide with polyclonal antibody PA5-20906.
靶标信息
BCAS3 is physically associated with histone H3 and histone acetyltransferase complex protein P/CAF (p300/CBP-associated factor) and possesses histone acetyltransferase activity. In breast cancer, several chromosomal sites frequently undergo amplification, implicating the location of genes important for tumor development and progression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BCAS3 microtubule associated cell migration factor; BCAS4/BCAS3 fusion; breast carcinoma amplified sequence 3; breast carcinoma amplified sequence 4/3 fusion protein; Breast carcinoma-amplified sequence 3; GAOB1; Maab1 protein; metastasis associated antigen of breast cancer; protein Maab1; Rudhira
基因别名: BCAS3; GAOB1; MAAB
UniProt ID: (Human) Q9H6U6
Entrez Gene ID: (Human) 54828
angiogenesis
transcription, DNA-templated
Golgi organization
positive regulation of endothelial cell migration
vesicle-mediated transport
microtubule organizing center organization
negative regulation of GTPase activity
tube formation
response to starvation
positive regulation of catalytic activity
positive regulation of GTPase activity
positive regulation of transcription from RNA polymerase II promoter
positive regulation of filopodium assembly
negative regulation of focal adhesion assembly
cellular response to estrogen stimulus
positive regulation of intracellular protein transport
activation of GTPase activity
regulation of establishment of cell polarity
positive regulation of actin cytoskeleton reorganization
