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产品信息
PEP-1475
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
对照试剂 (Ctrl) |
Assay-dependent | - |
阻断反应 (BLOCK) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Not Applicable |
分类 |
Synthetic |
类型 |
Peptide |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
200 µg/mL |
纯化类型 |
purified |
保存液 |
PBS, pH 7.2, with 0.1% BSA |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
产品详细信息
This peptide corresponds to 18 amino acid peptide near the carboxy terminus of human DLK1.
PEP-1475 can be used as a blocking peptide with polyclonal antibody PA5-34433.
靶标信息
The Delta-like 1 homolog (DLK1) is a transmembrane protein containing six epidermal growth factor repeats. It is involved in the differentiation of several cell types, including adipocytes and is also thought to be a tumor suppressor. The DLK1 gene is one of several imprinted genes located in a region on chromosome 14q32; certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). DLK1 is expressed from the paternal allele; a polymorphism within this gene has been associated with child and adolescent obesity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: delta-like 1 homolog; DLK-1; FA1; Fetal antigen 1; pG2; preadipocyte factor 1; PREF; Protein delta homolog 1; secredeltin
基因别名: Delta1; DLK; DLK-1; DLK1; FA1; pG2; Pref-1; PREF1; ZOG
UniProt ID: (Human) P80370
Entrez Gene ID: (Human) 8788
分子生物学功能:
membrane-bound signaling molecule
