Invitrogen

Human FOXH1 Synthetic Peptide

产品信息

PEP-1516

应用	建议稀释比	已发表文章
对照试剂 (Ctrl)	Assay-dependent	-
阻断反应 (BLOCK)	Assay-dependent	-

产品规格
种属反应	Human
宿主/亚型	Not Applicable
分类	Synthetic
类型	Peptide
偶联物	Unconjugated
形式	Liquid
浓度	200 µg/mL
纯化类型	purified
保存液	PBS, pH 7.2, with 0.1% BSA
内含物	0.02% sodium azide
保存条件	-20°C

产品详细信息

This peptide corresponds to 19 amino acids near the amino terminus of human FOXH1.

PEP-1516 can be used as a blocking peptide with polyclonal antibody PA5-34474.

靶标信息

FOXH1 is a member of the Forkhead-box (FOX) family of transcription factors and is the human homolog of Xenopus forkhead activin signal transducer-1. FOXH1 plays an important role in mediating TGF-beta/activin signals through its interaction with the SMAD2-SMAD4 complex. It is expressed primarily during early development and localizes in the cytoplasm until it forms a complex with the SMAD proteins at which time it translocates to the nucleus to positively or negatively affect gene expression.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: Fast-1; Fast-2; Forkhead activin signal transducer 1; Forkhead activin signal transducer 2; forkhead activin signal transducer-1; Forkhead box protein H1; hFAST-1; TGF-beta/activin signal transducer

基因别名: FAST-1; FAST1; FAST2; FOXH1

UniProt ID: (Human) O75593

Entrez Gene ID: (Human) 8928

功能

negative regulation of transcription from RNA polymerase II promoter heart looping secondary heart field specification outflow tract morphogenesis cardiac right ventricle morphogenesis ventricular trabecula myocardium morphogenesis transcription from RNA polymerase II promoter transforming growth factor beta receptor signaling pathway negative regulation of intracellular estrogen receptor signaling pathway embryonic heart tube anterior/posterior pattern specification aorta morphogenesis positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter axial mesoderm development negative regulation of androgen receptor signaling pathway nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry negative regulation of androgen receptor activity

参与通路

RNA polymerase II transcription factor activity, sequence-specific DNA binding RNA polymerase II transcription cofactor activity transcriptional activator activity, RNA polymerase II transcription factor binding transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding protein domain specific binding enhancer binding bHLH transcription factor binding sequence-specific DNA binding transcription regulatory region DNA binding SMAD binding androgen receptor binding co-SMAD binding R-SMAD binding

Human FOXH1 Synthetic Peptide

产品信息

PEP-1516

对照试剂 (Ctrl)

阻断反应 (BLOCK)

种属反应

宿主/亚型

分类

类型

偶联物

形式

浓度

纯化类型

保存液

内含物

保存条件

产品详细信息

靶标信息

篇参考文献 (0)

生物信息学

性能保障

随时为您服务

Your items have has been added!