Invitrogen

Human GBP5 Synthetic Peptide

产品信息

PEP-1584

应用	建议稀释比	已发表文章
对照试剂 (Ctrl)	Assay-dependent	-
阻断反应 (BLOCK)	Assay-dependent	-

产品规格
种属反应	Human
宿主/亚型	Not Applicable
分类	Synthetic
类型	Peptide
偶联物	Unconjugated
形式	Liquid
浓度	200 µg/mL
纯化类型	purified
保存液	PBS, pH 7.2, with 0.1% BSA
内含物	0.02% sodium azide
保存条件	-20°C

产品详细信息

This peptide corresponds to 16 amino acids near the carboxy terminus of human GBP5.

PEP-1584 can be used as a blocking peptide with polyclonal antibody PA5-34541. For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37°C.

靶标信息

The guanylate-binding proteins (GBPs) are a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN). GBP5 promotes selective NALP3 inflammasome responses to pathogenic bacteria and soluble but not crystalline inflammasome priming agents.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: GBP-5; GBP-TA antigen; GTP-binding protein 5; Guanine nucleotide-binding protein 5; Guanylate-binding protein 5

基因别名: GBP-5; GBP5; UNQ2427/PRO4987

UniProt ID: (Human) Q96PP8

Entrez Gene ID: (Human) 115362

分子生物学功能: heterotrimeric G-protein

功能

inflammatory response positive regulation of innate immune response interleukin-1 beta secretion protein homotetramerization cellular response to interferon-gamma interleukin-18 secretion positive regulation of cytokine production involved in inflammatory response positive regulation of NLRP3 inflammasome complex assembly

参与通路

GTPase activity protein binding GTP binding identical protein binding

Human GBP5 Synthetic Peptide

产品信息

PEP-1584

对照试剂 (Ctrl)

阻断反应 (BLOCK)

种属反应

宿主/亚型

分类

类型

偶联物

形式

浓度

纯化类型

保存液

内含物

保存条件

产品详细信息

靶标信息

篇参考文献 (0)

生物信息学

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