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产品信息
PEP-0714
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
对照试剂 (Ctrl) |
Assay-dependent | - |
阻断反应 (BLOCK) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Not Applicable |
分类 |
Synthetic |
类型 |
Peptide |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
200 µg/mL |
纯化类型 |
purified |
保存液 |
PBS, pH 7.2, with 0.1% BSA |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
产品详细信息
This peptide corresponds to 13 amino acids near the center of human IL-34
PEP-0714 can be used as a blocking peptide with polyclonal antibody PA5-20594.
靶标信息
IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor, also known as CSF-1R and CD115, which is shared with M-CSF. IL-34 has no amino acid sequence homology to M-CSF, but they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: IL-34; ILN; Interleukin; Interleukin-34; Interleukin34
基因别名: C16orf77; IL-34; IL34
UniProt ID: (Human) Q6ZMJ4
Entrez Gene ID: (Human) 146433
分子生物学功能:
interleukin superfamily
