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Invitrogen
Human IL-6R (soluble) Recombinant Protein
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产品信息
RP-75602
产品规格
Expression System
E. coli
分类
Recombinant
类型
Protein
偶联物
形式
Liquid
浓度
0.05 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
RP-75602 contains purified recombinant human IL-6 Soluble Receptor protein with an N-terminal hexahistidine tag.
RP-75602 may be used as a positive control in many immunological assays.
靶标信息
Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor. This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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