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产品信息
PEP-0929
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
对照试剂 (Ctrl) |
Assay-dependent | - |
阻断反应 (BLOCK) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Not Applicable |
分类 |
Synthetic |
类型 |
Peptide |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
200 µg/mL |
纯化类型 |
purified |
保存液 |
PBS, pH 7.2, with 0.1% BSA |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
产品详细信息
This peptide corresponds to 16 amino acids near the center of human JMJD2B.
PEP-0929 can be used as a blocking peptide with polyclonal antibody PA5-20815.
靶标信息
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: [histone H3]-trimethyl-L-lysine(9) demethylase 4B; JmjC domain-containing histone demethylation protein 3B; jumonji domain containing 2B; Jumonji domain-containing protein 2B; lysine (K)-specific demethylase 4B; Lysine-specific demethylase 4B; tudor domain containing 14B
基因别名: JHDM3B; JMJD2B; KDM4B; KIAA0876; TDRD14B
UniProt ID: (Human) O94953
Entrez Gene ID: (Human) 23030
分子生物学功能:
histone modifying enzyme
