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产品信息
PEP-0922
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
对照试剂 (Ctrl) |
Assay-dependent | - |
阻断反应 (BLOCK) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Not Applicable |
分类 |
Synthetic |
类型 |
Peptide |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
200 µg/mL |
纯化类型 |
purified |
保存液 |
PBS, pH 7.2, with 0.1% BSA |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
产品详细信息
This peptide corresponds to 15 amino acids near the amino terminus of human JMJD6.
PEP-0922 can be used as a blocking peptide with polyclonal antibody PA5-20808.
靶标信息
This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; Histone arginine demethylase JMJD6; JmjC domain-containing protein 6; jumonji domain containing 6; Jumonji domain-containing protein 6; Lysyl-hydroxylase JMJD6; Peptide-lysine 5-dioxygenase JMJD6; Phosphatidylserine receptor; Protein PTDSR
基因别名: JMJD6; KIAA0585; PSR; PTDSR; PTDSR1
UniProt ID: (Human) Q6NYC1
Entrez Gene ID: (Human) 23210
分子生物学功能:
protein modifying enzyme
kidney development
sprouting angiogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
mRNA processing
cell surface receptor signaling pathway
heart development
RNA splicing
peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine
lung development
T cell differentiation in thymus
macrophage activation
recognition of apoptotic cell
regulation of mRNA splicing, via spliceosome
erythrocyte development
oxidation-reduction process
retina development in camera-type eye
histone H3-R2 demethylation
histone H4-R3 demethylation
RNA binding
single-stranded RNA binding
receptor activity
iron ion binding
protein binding
histone demethylase activity
histone demethylase activity (H3-R2 specific)
histone demethylase activity (H4-R3 specific)
identical protein binding
protein homodimerization activity
peptidyl-lysine 5-dioxygenase activity
