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产品信息
PEP-0120
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
对照试剂 (Ctrl) |
Assay-dependent | - |
阻断反应 (BLOCK) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Not Applicable |
分类 |
Synthetic |
类型 |
Peptide |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
200 µg/mL |
纯化类型 |
purified |
保存液 |
PBS, pH 7.2, with 0.1% BSA |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
产品详细信息
This peptide corresponds to 14 amino acids near the amino terminus of human KLHL1
PEP-0120 can be used as a blocking peptide with polyclonal antibody PA5-19998.
靶标信息
The mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin-organizing proteins. Based on the presence of anti-sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ30047; kelch-like family member 1; Kelch-like protein 1; Mayven-related protein 2; RP11-394C23.1
基因别名: KIAA1490; KLHL1; MRP2
UniProt ID: (Human) Q9NR64
Entrez Gene ID: (Human) 57626
分子生物学功能:
scaffold/adaptor protein
