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产品信息
PEP-1147
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
对照试剂 (Ctrl) |
Assay-dependent | - |
阻断反应 (BLOCK) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Not Applicable |
分类 |
Synthetic |
类型 |
Peptide |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
200 µg/mL |
纯化类型 |
purified |
保存液 |
PBS, pH 7.2, with 0.1% BSA |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
产品详细信息
This peptide corresponds to 15 amino acids near the amino terminus of human KPNA4.
PEP-1147 can be used as a blocking peptide with polyclonal antibody PA5-21033.
靶标信息
The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Importin alpha Q1; Importin subunit alpha-3; importin subunit alpha-4; importin-alpha-Q1; karyopherin alpha 4; karyopherin alpha 4 (importin alpha 3); Karyopherin subunit alpha-4; MGC12217; MGC26703; Qip1; Qip1 protein
基因别名: IPOA3; KPNA4; QIP1; SRP3
UniProt ID: (Human) O00629
Entrez Gene ID: (Human) 3840
分子生物学功能:
transporter
