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产品信息
PEP-0691
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
对照试剂 (Ctrl) |
Assay-dependent | - |
阻断反应 (BLOCK) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Not Applicable |
分类 |
Synthetic |
类型 |
Peptide |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
200 µg/mL |
纯化类型 |
purified |
保存液 |
PBS, pH 7.2, with 0.1% BSA |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
产品详细信息
This peptide corresponds to 17 amino acids near the carboxy terminus of human MED4.
PEP-0691 can be used as a blocking peptide with polyclonal antibody PA5-20571.
靶标信息
The Mediator is a multiprotein coactivator that is required by DNA-binding transcription factors for activation of polymerase II transcribed genes. MED4 appears to be a core Mediator subunit and is found in nearly all Mediator preparations (Sato et al., 2004).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Activator-recruited cofactor 36 kDa component; ARC36; DRIP36; FLJ10956; Mediator complex subunit 4; Mediator of RNA polymerase II transcription subunit 4; mediator, 34-kD subunit, homolog; RP11-90M2.2; TRAP/SMCC/PC2 subunit p36; TRAP/SMCC/PC2 subunit p36 subunit; vitamin D receptor-interacting protein, 36-kD; Vitamin D3 receptor-interacting protein complex 36 kDa component
基因别名: ARC36; DRIP36; HSPC126; MED4; TRAP36; VDRIP
UniProt ID: (Human) Q9NPJ6
Entrez Gene ID: (Human) 29079
分子生物学功能:
general transcription factor
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
intracellular steroid hormone receptor signaling pathway
androgen receptor signaling pathway
positive regulation of transcription, DNA-templated
