Invitrogen

Human/Mouse ITIH2 Synthetic Peptide

产品信息

PEP-302

应用	建议稀释比	已发表文章
对照试剂 (Ctrl)	Assay-dependent	-
阻断反应 (BLOCK)	Assay-dependent	-

产品规格
种属反应	Human, Mouse
宿主/亚型	Not Applicable
分类	Synthetic
类型	Peptide
偶联物	Unconjugated
形式	Lyophilized
浓度	1 mg/mL
纯化类型	purified
保存液	water
内含物	no preservative
保存条件	-20°C

产品详细信息

This peptide corresponds to amino acids E(401) ANNLGLLDPN (411) of human ITI-HC2 and can be used as a blocking peptide with polyclonal antibody PA1-1756. This product cross-reacts with mouse due to sequence homology.

靶标信息

The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis. The ITI family contains multiple proteins made up of a light chain (see MIM 176870) and a variable number of heavy chains (Salier et al., 1987 [PubMed 2446322]; Himmelfarb et al., 2004 [PubMed 14744536]). ITI-HC2 may act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: HC2; inter-alpha (globulin) inhibitor H2; inter-alpha (globulin) inhibitor, H2 polypeptide; inter-alpha-inhibitor heavy chain 2; Inter-alpha-trypsin inhibitor complex component II; Inter-alpha-trypsin inhibitor heavy chain H2; ITI heavy chain H2; ITI-HC2; PSMA1; Serum-derived hyaluronan-associated protein; SHAP

基因别名: AI747202; H2P; IGHEP2; Intin2; Itih-2; ITIH2; SHAP

UniProt ID: (Human) P19823, (Mouse) Q61703

Entrez Gene ID: (Human) 3698, (Mouse) 16425

分子生物学功能: protease inhibitor