Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
应用 | 建议稀释比 | 已发表文章 |
---|---|---|
对照试剂 (Ctrl) |
Assay-dependent | - |
阻断反应 (BLOCK) |
Assay-dependent | - |
产品规格 | |
---|---|
种属反应 |
Human |
宿主/亚型 |
Not Applicable |
分类 |
Synthetic |
类型 |
Peptide |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
200 µg/mL |
纯化类型 |
purified |
保存液 |
PBS, pH 7.2, with 0.1% BSA |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
This peptide corresponds to 15 amino acids near the carboxy terminus of human NENF
PEP-0697 can be used as a blocking peptide with polyclonal antibody PA5-20577.
NENF is a secreted protein that is expressed in neurons but not glial cells of the brain. This protein has neurotrophic activity in primary cultured mouse neurons but not mitogenic activity in primary cultured mouse astrocytes. NENF activated mitogen-activated protein (MAP) and phosphotidylinositol-3 kinase pathways and could be inhibited by pertussis toxin but not receptor tyrosine kinases, suggesting that NENF acts through a Gi/Go-protein-coupled receptor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: cell growth-inhibiting protein 47; Cell immortalization-related protein 2; Neudesin; Neuron-derived neurotrophic factor; Protein GIG47; SCIRP10-related protein; Secreted protein of unknown function; Spinal cord injury related protein 10; SPUF protein
基因别名: CIR2; NENF; SCIRP10; SPUF
UniProt ID: (Human) Q9UMX5
Entrez Gene ID: (Human) 29937
分子生物学功能:
transmembrane signal receptor