Invitrogen

Human PLAGL2 Synthetic Peptide

产品信息

PEP-1499

应用	建议稀释比	已发表文章
对照试剂 (Ctrl)	Assay-dependent	-
阻断反应 (BLOCK)	Assay-dependent	-

产品规格
种属反应	Human
宿主/亚型	Not Applicable
分类	Synthetic
类型	Peptide
偶联物	Unconjugated
形式	Liquid
浓度	200 µg/mL
纯化类型	purified
保存液	PBS, pH 7.2, with 0.1% BSA
内含物	0.02% sodium azide
保存条件	-20°C

产品详细信息

This peptide corresponds to 19 amino acids near the amino terminus of human PLAGL2.

PEP-1499 can be used as a blocking peptide with polyclonal antibody PA5-34457.

靶标信息

The PLAG (Pleiomorphic adenoma gene) family of zinc finger proteins include PLAG1, ZAC1 and PLAG-like 2 (PLAGL2). PLAG1 is the target gene for the pleiomorphic adenomas of the salivary gland. ZAC1 (PLAGL1) concomitantly controls apoptosis and cell cycle arrest through separate pathways. ZAC1 also acts as a transcriptional cofactor for nuclear receptors. PLAGL2 belongs to the krueppel C2H2-type zinc-finger protein family and contains 6 C2H2-type zinc fingers. It functions as a positive regulator of transcription and localizes to the nucleus. PLAGL2 is ubiquitously expressed with particular abundance in spleen, lung and testis, where it may be involved in cell cycle arrest and apoptosis of tumor cells.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: C2H2-type zinc finger protein; pleiomorphic adenoma gene-like 2; Pleiomorphic adenoma-like protein 2; Zinc finger protein PLAGL2

基因别名: KIAA0198; PLAGL2; ZNF900

UniProt ID: (Human) Q9UPG8

Entrez Gene ID: (Human) 5326

分子生物学功能: C2H2 zinc finger transcription factor

功能

transcription from RNA polymerase II promoter lipid metabolic process post-embryonic development chylomicron assembly positive regulation of transcription from RNA polymerase II promoter positive regulation of protein targeting to mitochondrion positive regulation of intrinsic apoptotic signaling pathway

参与通路

transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, sequence-specific DNA binding sequence-specific DNA binding metal ion binding

Human PLAGL2 Synthetic Peptide

产品信息

PEP-1499

对照试剂 (Ctrl)

阻断反应 (BLOCK)

种属反应

宿主/亚型

分类

类型

偶联物

形式

浓度

纯化类型

保存液

内含物

保存条件

产品详细信息

靶标信息

篇参考文献 (0)

生物信息学

性能保障

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