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产品信息
PEP-0964
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
对照试剂 (Ctrl) |
Assay-dependent | - |
阻断反应 (BLOCK) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Not Applicable |
分类 |
Synthetic |
类型 |
Peptide |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
200 µg/mL |
纯化类型 |
purified |
保存液 |
PBS, pH 7.2, with 0.1% BSA |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
产品详细信息
This peptide corresponds to 17 amino acids near the carboxy terminus of human PLEKHM2.
PEP-0964 can be used as a blocking peptide with polyclonal antibody PA5-20850.
靶标信息
PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: novel RUN and PH domain-containing protein; PH domain-containing family M member 2; pleckstrin homology domain containing, family M (with RUN domain) member 2; Pleckstrin homology domain-containing family M member 2; RP11-169K16.1; Salmonella-induced filaments A and kinesin-interacting protein; SifA (Salmonella-induced filaments A) and kinesin-interacting protein; SifA and kinesin-interacting protein
基因别名: KIAA0842; PLEKHM2; SKIP
UniProt ID: (Human) Q8IWE5
Entrez Gene ID: (Human) 23207
