Invitrogen

Human RANBP2 (aa 1-18) Synthetic Peptide

产品信息

PEP-137

应用	建议稀释比	已发表文章
对照试剂 (Ctrl)	Assay-dependent	-

产品规格
种属反应	Human
宿主/亚型	Not Applicable
分类	Synthetic
类型	Peptide
偶联物	Unconjugated
形式	Lyophilized
浓度	0.5 mg/mL
纯化类型	purified
内含物	no preservative
保存条件	-20° C, Avoid Freeze/Thaw Cycles

产品详细信息

PEP-137 is an 18 amino acid synthetic peptide whose sequences are derived from human RanBP2 protein. The sequence of this peptide is (amino to carboxy terminus): M (1)-R-R-S-K-A-D-V-E-R-Y-I-A-S-V-Q-G-S (18)-C

This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human RanBP2, catalog # PA1-082. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.

Reconstitute with 0.1 mL of distilled water.

靶标信息

RanBP2 interacts with the small GTP-binding protein Ran and forms a large multiprotein complex involved in many biological processes such as mRNA processing, nuclear transport, cell cycle control and postmitotic nuclear reassembly. The protein is identified by western blotting as an apparent molecular mass of 360 kD. It is involved in nucleation of microtubule and control of cell growth by interacting with many protein factors.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: 358 kDa nucleoporin; acute necrotizing encephalopathy 1 (autosomal dominant); E3 SUMO-protein ligase RanBP2; Nuclear pore complex protein Nup358; nucleoporin 358; Nucleoporin Nup358; P270; Ran-binding protein 2; RanBP2; RBP2; transformation-related protein 2

基因别名: ADANE; ANE1; IIAE3; NUP358; RANBP2; TRP1; TRP2

UniProt ID: (Human) P49792

Entrez Gene ID: (Human) 5903

分子生物学功能: chaperone scaffold/adaptor protein