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产品信息
PEP-0523
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
对照试剂 (Ctrl) |
Assay-dependent | - |
阻断反应 (BLOCK) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Not Applicable |
分类 |
Synthetic |
类型 |
Peptide |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
200 µg/mL |
纯化类型 |
purified |
保存液 |
PBS, pH 7.2, with 0.1% BSA |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
产品详细信息
This peptide corresponds to 15 amino acids near the amino terminus of human STEAP3.
PEP-0523 can be used as a blocking peptide with polyclonal antibody PA5-20406.
靶标信息
The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP4), STEAP3 promotes both iron and copper reduction. STEAP3 is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome. Overexpression of STEAP3 stimulates iron reduction; mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 is an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: dudlin 2; Dudulin-2; hpHyde; hTSAP6; Metalloreductase STEAP3; pHyde; Six-transmembrane epithelial antigen of prostate 3; STEAP family member 3, metalloreductase; tumor suppressor pHyde; Tumor suppressor-activated pathway protein 6
基因别名: AHMIO2; dudlin-2; dudulin-2; pHyde; STEAP3; STMP3; TSAP6
UniProt ID: (Human) Q658P3
Entrez Gene ID: (Human) 55240
