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产品信息
PEP-1072
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
对照试剂 (Ctrl) |
Assay-dependent | - |
阻断反应 (BLOCK) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Not Applicable |
分类 |
Synthetic |
类型 |
Peptide |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
200 µg/mL |
纯化类型 |
purified |
保存液 |
PBS, pH 7.2, with 0.1% BSA |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
产品详细信息
This peptide corresponds to 18 amino acids near the carboxy terminus of human SAE2.
PEP-1072 can be used as a blocking peptide with polyclonal antibody PA5-20958.
靶标信息
UBA2 is involved in covalent attachment of one protein to another is one of the more prominent posttranslational modifications in respect to size and ubiquity. Ubiquitin is the most familiar of the protein modifiers and its activation and transfer to target proteins has been studied extensively. Recently, a new group of ubiquitin-like proteins has been receiving a lot of attention. SUMO, or Sentrin, is one of the most intriguing. SUMO has been implicated in the stabilization of target proteins and/or their localization to sub-cellular complexes.The conjugation of SUMO-1, SUMO-2 and SUMO-3 onto target proteins requires the concerted action of the specific E1-activating enzyme SAE1/SAE2, the E2-conjugating enzyme Ubc9, and an E3-like SUMO ligase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Anthracycline-associated resistance ARX; FLJ13058; SUMO-1 activating enzyme subunit 2; SUMO-activating enzyme subunit 2; SUMO1 activating enzyme subunit 2; UBA2, ubiquitin-activating enzyme E1 homolog; Ubiquitin-like 1-activating enzyme E1B; ubiquitin-like modifier activating enzyme 2; Ubiquitin-like modifier-activating enzyme 2
基因别名: ARX; HRIHFB2115; SAE2; UBA2; UBLE1B
UniProt ID: (Human) Q9UBT2
Entrez Gene ID: (Human) 10054
分子生物学功能:
DNA-binding transcription factor
ubiquitin-protein ligase
