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产品信息
PEP-1041
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
对照试剂 (Ctrl) |
Assay-dependent | - |
阻断反应 (BLOCK) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Not Applicable |
分类 |
Synthetic |
类型 |
Peptide |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
200 µg/mL |
纯化类型 |
purified |
保存液 |
PBS, pH 7.2, with 0.1% BSA |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
产品详细信息
This peptide corresponds to 17 amino acids near the amino terminus of human ZC3H12B.
PEP-1041 can be used as a blocking peptide with polyclonal antibody PA5-20927.
靶标信息
ZC3H12B, also known as MCPIP2, is a member of a family of novel CCCH-zinc finger proteins that regulate macrophage activation and may be involved in host immunity and inflammatory diseases. The function of ZC3H12B is not well understood. Unlike other members of the ZC3H12 family, ZC3H12B has a RasGEF domain at the C-terminal of the zinc finger motif, suggesting its potential involvement in Ras-mediated signal transduction. It is highly expressed in brain, thymus, and testis, but unlike ZC3H12A and ZC3H12C, not expressed in macrophages after treatment with lipopolysaccharide (LPS).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MCP-induced protein 2; Probable ribonuclease ZC3H12B; RP3-475B7.1; Zinc finger CCCH domain-containing protein 12B
基因别名: CXorf32; MCPIP2; ZC3H12B
UniProt ID: (Human) Q5HYM0
Entrez Gene ID: (Human) 340554
分子生物学功能:
endoribonuclease
