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产品信息
PEP-1459
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
对照试剂 (Ctrl) |
Assay-dependent | - |
阻断反应 (BLOCK) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Not Applicable |
分类 |
Synthetic |
类型 |
Peptide |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
200 µg/mL |
纯化类型 |
purified |
保存液 |
PBS, pH 7.2, with 0.1% BSA |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
产品详细信息
This peptide corresponds to 17 amino acid peptide near the carboxy terminus of human ZMYM4.
PEP-1459 can be used as a blocking peptide with polyclonal antibody PA5-34417.
靶标信息
Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. It has been found to be overexpressed in human lung adenocarcinomas and squamous cell carcinomas, and the overexpression of a fragment of the 3'UTR of the ZMYM4 mRNA termed Cell Death Inhibiting RNA (CDIR) protects HeLa cells from IFN-gamma-induced apoptosis, suggesting that ZMYM4 may play a role in tumorigenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cell death inhibiting RNA; MYM type 4; Zinc finger MYM-type protein 4; Zinc finger protein 262; zinc finger, MYM-type 4
基因别名: CDIR; KIAA0425; MYM; ZMYM4; ZNF198L3; ZNF262
UniProt ID: (Human) Q5VZL5
Entrez Gene ID: (Human) 9202
分子生物学功能:
zinc finger transcription factor
