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Invitrogen
Human c-Fos Synthetic Peptide
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产品信息
GSC00001P
产品规格
分类
Synthetic
类型
Peptide
偶联物
形式
Lyophilized
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
GSC00001P is the immunizing peptide for the rabbit antibody to cFos (OSR00004W & OSC00007W).
GSC00001P may be used as a control in various immunology applications.
Reconstitute with PBS or distilled water.
Store antibody at 4°C up to 12 months. After reconstitution, store at -20°C. Avoid freeze and thaw cycles.
靶标信息
FBJ murine osteosarcoma viral oncogene homolog is commonly known as Cellular protooncogene Fos (c-Fos). It belongs to the fos transcription factor family and is encoded by the C-FOS gene located on chromosome 14. c-Fos heterodimerizes with c-Jun to form the Activator Protein -1 (AP-1) transcription factor which regulates transcription of several genes that play an important role in cellular signal transduction, cell proliferation and differentiation. c-Fos has been shown to be phosphorylated by various stimuli including growth factors and insulin at atleast seven different sites. The best known upstream kinase for phosphorylation at Threonine 232 is ERK MAPK which regulates localization of c-Fos to the nucleus and is thus important for c-Fos induced transcriptional activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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