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Invitrogen
IARS Polyclonal Antibody
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产品信息
PA5-56267
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human IARS
偶联物
形式
Liquid
浓度
0.05 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: NWYVRMNRRR LKGENGMEDC VMALETLFSV LLSLCRLMAP YTPFLTELMY QNLKVLIDPV SVQDKDTLSI HYLMLPRVRE ELIDKKTESA VSQMQSVIEL
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 93%.
靶标信息
IARS is a member of aminoacyl-tRNA synthetases which catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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