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Proteintech
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Immunogen sequence: VADQLLITRL KEICEVALTE KLTLKNAAML LEFAAMYSAK QLKLSCLQFI GLNMAALLEA RSLDVLSDGV LKDLSEFYRK MIPAMDRRVI TPYQDGPDIS YLEVEDGDIF LKEEINMEQN HSETMFKKAK TKAKKKPRKR SDSSGGYNLS D
The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Bruton agammaglobulinemia tyrosine kinase inhibitor; BTK-binding protein; IBtk; inhibitor of Bruton agammaglobulinemia tyrosine kinase; Inhibitor of Bruton tyrosine kinase; inhibitor of Bruton's tyrosine kinase-alpha; inhibitor of Bruton's tyrosine kinase-beta; inhibitor of Bruton's tyrosine kinase-gamma; RP1-93K22.1
基因别名: 5430411K16Rik; AA409502; BTBD26; BTKI; IBTK; KIAA1417; mKIAA1417
UniProt ID: (Human) Q9P2D0, (Mouse) Q6ZPR6
Entrez Gene ID: (Human) 25998, (Mouse) 108837, (Rat) 315858