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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: LKEICEVALT EKLTLKNAAM LLEFAAMYSA KQLKLSCLQF IGLNMAALLE ARSLDVLSDG VLKDLSEFYR KMIPAMDRRV ITPYQDGPDI SYLEVEDGDI FLKEEINMEQ NHSETMFKKA K
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 79%.
The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: IBtk; Inhibitor of Bruton tyrosine kinase; RP1-93K22.1
基因别名: BTKI; IBTK; KIAA1417
Entrez Gene ID: (Human) 25998