Invitrogen

ICAM-2 Monoclonal Antibody (3C4), Alexa Fluor™ 647

ICAM-2 Antibody in Flow Cytometry (Flow)

图: 1 / 1

ICAM-2 Antibody (A15452) in Flow

Flow cytometry analysis of ICAM-2 in BALB/c mouse splenocytes. Cells were stained using ICAM-2 Monoclonal Antibody (3C4), Alexa Fluor™ 647 (Product # A15452).

Product Image Gallery

产品信息

A15452

应用

建议稀释比

已发表文章

流式细胞分析 (Flow)

0.2 µg/1x10^6 cells

查看6篇已发表文章 6篇已发表文章

产品规格

种属反应

Mouse

已发表种属

Mouse

宿主/亚型

Rat / IgG2a, kappa

分类

Monoclonal

类型

Antibody

克隆号

3C4

抗原

Mouse CD102 from COS cells transfected with mouse ICAM-2 cDNA and BW5147 AKR/J mouse thymoma cell line

查看免疫原

偶联物

Alexa Fluor™ 647 Alexa Fluor™ 647 Alexa Fluor™ 647

激发/发射光谱

650/671 nm 查看光谱

形式

Liquid

浓度

0.5 mg/mL

纯化类型

purified

保存液

PBS, pH 7.4

内含物

<0.1% sodium azide

保存条件

4°C, store in dark

运输条件

Ambient (domestic); Wet ice (international)

AB_2534465

靶标信息

ICAM-2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. ICAM-2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. Diseases associated with ICAM2 include Colon Carcinoma In Situ.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

Product References

Three-axis classification of mouse lung mesenchymal cells reveals two populations of myofibroblasts.

Development (Cambridge, England)

Narvaez Del Pilar O,Gacha Garay MJ,Chen J

A15452 was used in Flow cytometry/Cell sorting to classify the mouse lung mesenchyme into three proximal-distal axes that are associated with the endothelium, epithelium and interstitium, respectively.

Tue Mar 15 00:00:00 UTC 2022

Differential chromatin binding of the lung lineage transcription factor NKX2-1 resolves opposing murine alveolar cell fates in vivo.

Nature communications

Little DR,Lynch AM,Yan Y,Akiyama H,Kimura S,Chen J

A15452 was used in Flow cytometry/Cell sorting to report that the cell-type-specific function of NKX2-1 is attributed to its differential chromatin binding that is acquired or retained during development in coordination with partner transcriptional factors.

Tue May 04 00:00:00 UTC 2021

Single-Cell RNA Sequencing Reveals Renal Endothelium Heterogeneity and Metabolic Adaptation to Water Deprivation.

Journal of the American Society of Nephrology : JASN

Dumas SJ,Meta E,Borri M,Goveia J,Rohlenova K,Conchinha NV,Falkenberg K,Teuwen LA,de Rooij L,Kalucka J,Chen R,Khan S,Taverna F,Lu W,Parys M,De Legher C,Vinckier S,Karakach TK,Schoonjans L,Lin L,Bolund L,Dewerchin M,Eelen G,Rabelink TJ,Li X,Luo Y,Carmeliet P

A15452 was used in Flow cytometry/Cell sorting to provide a high-resolution atlas of the renal endothelium and highlights extensive renal endothelial cell phenotypic heterogeneity, as well as a previously unrecognized role of oxidative phosphorylation in the metabolic adaptation of medullary renal endothelial cells to water deprivation.

Wed Jan 01 00:00:00 UTC 2020

Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung.

Developmental cell

Vila Ellis L,Cain MP,Hutchison V,Flodby P,Crandall ED,Borok Z,Zhou B,Ostrin EJ,Wythe JD,Chen J

A15452 was used in Flow cytometry/Cell sorting to show that VEGFA from the epithelium is required for a distinct endothelial cell (EC) population in the mouse lung.

Mon Mar 09 00:00:00 UTC 2020

Redundant and additive functions of the four Lef/Tcf transcription factors in lung epithelial progenitors.

Proceedings of the National Academy of Sciences of the United States of America

Gerner-Mauro KN,Akiyama H,Chen J

A15452 was used in Flow cytometry/Cell sorting to generate two quadruple conditional knockouts, four triple mutants, and various combinations of double mutants, showing that the four Lef/Tcf genes function redundantly in the presence of at least two Lef/Tcf paralogs, but additively upon losing additional paralogs to specify and maintain lung epithelial progenitors., using the developing mouse lung as a model system.

Tue Jun 02 00:00:00 UTC 2020

Quantitative single-cell interactomes in normal and virus-infected mouse lungs.

Disease models & mechanisms

Cain MP,Hernandez BJ,Chen J

A15452 was used in Flow cytometry/Cell sorting to describe a quantitative intuitive algorithm, coupled with an optimized experimental protocol, to construct and compare interactomes as a Control and Sendai virus-infected mouse lungs.