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Invitrogen
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Immunogen sequence: KTLRGPGWVSY QLLDVRAWSS LAHCLVTCAG KTRWATSRIT AYKPPHSVIL EPPVLKGRKY TLRCHVTQ
Highest antigen sequence identity to the following orthologs - mouse 74%, rat 72%.
This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。