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Antibody detects endogenous levels of total ICAM5.
The protein encoded by this gene is a member of the intercellular adhesion molecule family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ICAM-5; intercellular adhesion molecule 3; Intercellular adhesion molecule 5; intercellular adhesion molecule 5, telencephalin; Telencephalin
基因别名: CD50; ICAM-3; Icam3; ICAM5; TLCN; TLN
UniProt ID: (Human) Q9UMF0, (Mouse) Q60625
Entrez Gene ID: (Human) 7087, (Mouse) 15898, (Rat) 313785