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Invitrogen
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Immunogen sequence: ALSPELGASN FNDQKSSGIE YTKVVKGLTK IHSLPRSVFM KATKDGQCES QDPRIELTLN KPDFTSLIGS QAALIKSGLG FVKSTSWHHS DLLRKGG
Highest antigen sequence identity to the following orthologs: Mouse - 48%, Rat - 46%.
Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968, PubMed:23932780). Specifically acts as a scaffold protein that promotes the LEC complex formation and recruitment and RNA polymerase II occupancy at snRNA genes in subnuclear bodies (PubMed:23932780).
仅用于科研。不用于诊断过程。未经明确授权不得转售。