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Immunogen sequence: NKGSGTWEEKP KSHEAIQALN TWEVNKVTTS GLETFTATLR ESSATHSLVG EKHWTTASRS MSDRKRDILH ETKTQMEVRE MDKSVQTEKT IH
Highest antigen sequence identity to the following orthologs - mouse 40%, rat 31%.
Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968, PubMed:23932780). Specifically acts as a scaffold protein that promotes the LEC complex formation and recruitment and RNA polymerase II occupancy at snRNA genes in subnuclear bodies (PubMed:23932780).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Interactor of little elongator complex ELL subunit 1; Little elongation complex subunit 1
基因别名: ICE1; KIAA0947
UniProt ID: (Human) Q9Y2F5
Entrez Gene ID: (Human) 23379
分子生物学功能: protein modifying enzyme