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Peptide sequence: GSNFNHVVQN EKSDTHTLVT SGVYAWFRHP SYVGWFYWSI GTQVMLCNPI
Sequence homology: Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 79%
This gene encodes the third of three enzymes that post translationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
Protein Aliases: Isoprenylcysteine carboxylmethyltransferase; MGC39955; pcCMT; PPMT; Prenylated protein carboxyl methyltransferase; Prenylcysteine carboxyl methyltransferase; protein-S isoprenylcysteine O-methyltransferase; Protein-S-isoprenylcysteine O-methyltransferase
Gene Aliases: HSTE14; ICMT; MST098; MSTP098; PCCMT; PCMT; PPMT
UniProt ID: (Human) O60725
Entrez Gene ID: (Human) 23463
Molecular Function:
protein modifying enzyme
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