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Invitrogen
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Positive Control: NCCIT cell lysates, human fetal skeletal muscle tissue, human kidney tissue, mouse colon tissue, mouse lung tissue, HepG2.
Subcellular Location: Cytoplasm, Nucleus.
The inhibitor of DNA binding 2 (ID2) protein is essential for promoting the development of a number of cell types including natural killer cell, erythroid precursors, as well as, CD8+ and CD4+ T-cell. A lack of ID2 promotes B-cell development. The chief role of this protein is to associate with ubiquitously-expressed E proteins, and other proteins of the basic helix-loop-helix (HLH) family, preventing them from binding to DNA and activating transcription. Activation of ID2 is critical for the development of the natural killer cell lineage.
仅用于科研。不用于诊断过程。未经明确授权不得转售。